What aspect is NOT included in defining controlled substance analogs?

The definition of controlled substance analogs includes various aspects that characterize how these substances are treated under the law. Among these, the absence of legal approval for all substances is a critical point. Controlled substance analogs are typically substances that have a similar chemical structure to a controlled substance or produce effects on the central nervous system that are comparable to those of controlled substances.

Legal approval is not a defining factor in determining whether a substance is categorized as an analog. Even if a substance mimics the effects of controlled drugs or shares a similar chemical structure, it may not necessarily have undergone the legal approval process. Therefore, the lack of legal approval signifies that not all similar compounds are sanctioned or regulated, but if they meet defined criteria regarding their chemical structure or effects, they can still be considered analogs regardless of their legal status.

This highlights the distinction between analogs and legally sanctioned substances, clarifying that the presence of legal approval is not an aspect of what constitutes controlled substance analogs.